Pax Naturals Melatonin Sleeping Aid Tablets, Helps You Fall Asleep Faster, Deep Sleep, Faster Absorption, 10 mg - 30 Tablets

• Jet lag problems.
• Insomnia issues.
• Shift-work disorder problems.
• Circadian rhythm disorders in the blind.
• Sleep-wake cycle disturbances.
• Central nervous system disorders.
• Autism problem.

Important Information Regarding Melatonin

• Melatonin is a biogenic amine that is found in creatures, plants and organisms.
• Likewise a viable cancer prevention agent.
• It is a hormone, delivered in the mind, that completes a wide scope of jobs in the body; the most notable of its capacities is the control of circadian (day-by-day) rhythms.
• Created in the pineal organ in the cerebrum, melatonin enables control to rest wake cycles.

MECHANISM OF ACTION:-

• Melatonin is a subordinate of tryptophan. It ties to melatonin receptor type 1A, which at that point follows up on adenylate cyclase and the restraint of a cAMP sign transduction pathway.
• Melatonin represses adenylate cyclase, yet it likewise initiates phospholipase C. This potentiates the arrival of arachidonate.
• By authoritative to melatonin receptors 1 and 2, the downstream signaling falls have different impacts on the body.
• The melatonin receptors are G protein-coupled receptors and are communicated in different tissues of the body. There are two subtypes of the receptor in people, melatonin receptor 1 (MT1) and melatonin receptor 2 (MT2).
• Melatonin and melatonin receptor agonists, on showcase or in clinical preliminaries, all predicament to and enact both receptor types. When melatonin receptor agonists tie to and initiate their receptors it causes various physiological procedures.
• MT1 receptors are communicated in numerous locales of the focal sensory system (CNS): the suprachiasmatic core of the nerve center (SNC), hippocampus, substantianigra, cerebellum, focal dopaminergic pathways, ventral tegmental territory, and core accumbens. MT1 is likewise communicated in the retina, ovary, testis, mammary organ, coronary flow and aorta, gallbladder, liver, kidney, skin, and the safe framework.

SIDE-EFFECTS:-

• Headache
• Short-term feelings of depression
• Daytime sleepiness
• Dizziness
• Stomach cramps
• Irritability

CONTRAINDICATIONS:-

• Melatonin isn't suggested for pregnant or breastfeeding ladies.
• Alert is exhorted for dialysis patients because of the danger of expanded antagonistic impacts because of the failure to sufficiently clear melatonin.
• Alert is prompted for patients with weakened liver working because of diminished capacity to use melatonin.

Manufacturer: Rainbow Human Care Pvt. Ltd.

Address: Vill.- Bhud, NH-21A, Baddi, Distt-Solan, Solan(H.P) 173205

Net Weight in (Grams):